The “reward hub”, which is involved in addiction, was larger in the brains of people who regularly play computer games versus  those of infrequent gamers, research suggests. However, it remains unclear whether frequent use of the games changed the brain or if brain differences made people more likely to play:

http://www.nature.com/tp/journal/v1/n11/full/tp201153a.html

http://www.bbc.co.uk/news/health-15720178

http://www.dailymail.co.uk/sciencetech/article-2061983/Teenage-video-game-players-brains-like-gambling-addicts.html?ITO=1490

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